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MELANOCORTIN LIGANDS

Afamelanotide

$99.99 $108.99
Limited Batch Pricing
Ends Monday, Jun 8 at 12:59 AM EDT
Free worldwide shipping HPLC ≥97% purity COA included
For research use only. Not intended for human consumption.

About this compound

Selective MC1R agonist for clean melanin stimulation. FDA-approved photoprotective peptide. Tanning benefits without broad melanocortin side effects.

Product Details

Afamelanotide (NDP-MSH / Melanotan I) is a synthetic peptide with a molecular weight of 1646.85 g/mol and molecular formula C78H111N21O19. Supplied as a lyophilised solid, each batch is verified to ≥98% purity via HPLC analysis and accompanied by a Certificate of Analysis (COA).

Afamelanotide (NDP-MSH / Melanotan I) is soluble in water. For optimal stability, store the unopened vial at -20 °C, desiccated, protected from light. Stable for up to 21 days at 2–8 °C in aqueous solution under sterile conditions.

Afamelanotide (also known as Melanotan I) is a synthetic analog of alpha-melanocyte-stimulating hormone (alpha-MSH) that activates the MC1R receptor to stimulate melanin production. Unlike Melanotan II, Afamelanotide is highly selective for the MC1R receptor, providing tanning and photoprotective benefits without the broader side effects associated with MC2-MC5 receptor activation. It is the first melanocortin-based drug to receive FDA approval (as Scenesse for erythropoietic protoporphyria).

Why LarnaLabs

Every compound we supply is synthesized in ISO-certified GMP facilities using automated solid-phase peptide synthesis, ensuring batch-to-batch consistency and accurate sequencing.

Each batch undergoes independent third-party testing — HPLC for purity verification (≥97%), mass spectrometry for identity confirmation, and endotoxin screening (<1 EU/μg). A full Certificate of Analysis ships with every order.

We offer free worldwide shipping with temperature-controlled packaging, anonymous checkout for your privacy, and responsive support from a team that understands research-grade compounds.

Identification
Molecular Weight (g/mol)1646.85
Molecular FormulaC78H111N21O19
Peptide SequenceAc-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Product NameAfamelanotide (NDP-MSH / Melanotan I)
Catalogue NumberLL-AFAM-10
CAS Number75921-69-6
Physical and Chemical Properties
Active IngredientAfamelanotide (NDP-MSH / Melanotan I)
AppearanceWhite lyophilised powder
FormLyophilised Solid
Purity (HPLC)≥98%
SolubilitySoluble in water
Analytical and Quality Control
Mass SpectrumConforms to specification (1646.85 g/mol)
Amino Acid CompositionConsistent with the theoretical peptide sequence
Endotoxin< 1 EU/μg by LAL method
Research Use and Safety
CautionHandle using appropriate PPE and in compliance with relevant laboratory safety standards.
Intended UseFor laboratory research use only. Not for human or veterinary use.
Hazard ClassificationNot classified as hazardous under GHS for research quantities
Storage, Handling and Stability
Storage Temperature, Opened-20 °C, minimise freeze-thaw cycles
Storage Temperature, Unopened-20 °C, desiccated, protected from light
Shelf Life2 years unopened under recommended conditions
Reconstitution StabilityStable for up to 21 days at 2–8 °C in aqueous solution under sterile conditions

Shipping

All orders include free worldwide shipping with tracking. Orders are dispatched within 1-2 business days and typically arrive within 5-10 business days depending on destination.

Shipments are temperature-controlled and packaged to maintain compound integrity during transit. Shipping protection is included at no extra cost.

Returns & Refunds

If your order arrives damaged or does not meet stated purity specifications, contact us within 14 days for a full replacement or refund. A COA discrepancy or verified shipping damage is required for processing.

All products are shipped in compliance with applicable regulations for research-use materials. Customs duties or import fees, if applicable, are the responsibility of the buyer.